Dr. Gafni received her BA from Barnard College and her MD from Temple University. She completed a pediatric residency at the Children's Hospital of Philadelphia followed by a pediatric endocrinology fellowship at the National Institute of Health (NIH), serving as an officer in the Public Health Service from 1996-2002. She subsequently served as an Assistant Professor at the University of Maryland. Dr. Gafni returned to NIH in 2007 as a staff clinician in the National Institute od Dental and Craniofacial Research. She is also faculty in the NIH Pediatric Endocrinology and NIH Inter-institute Adult Endocrinology Training Programs. She is an investigator on several protocols studying and treating patients with endocrine disorders including hypoparathyroidism, McCune-Albright Syndrome, hypophosphatemic rickets, hyperphosphatemic familial humoral calcinosis, generalized arterial calcification of infancy, and other metabolic bone diseases